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Fragile Histidine Triad Protein, Ww Domain-Containing Oxidoreductase Protein Wwox, And Activator Protein 2 Gamma Expression Levels Correlate With Basal Phenotype In Breast Cancer
(Wiley, 2009)
BACKGROUND: The expression of fragile histidine triad protein (Fhit) and WW domain-containing oxidor-eductase protein (Wwox), tumor suppressors that are encoded by fragile (FRA) loci FRA3B and FPA16D, are lost concordantly ...
Multicenter Analysis Of Gestational Trophoblastic Neoplasia In Turkey
(Asian Pacific Organization Cancer Prevention, 2014)
Background: To evaluate the incidence, diagnosis and management of GTN among 28 centers in Turkey. Materials and Methods: A retrospective study was designed to include GTN patients attending 28 centers in the 10-year period ...
Aberrant Expression of Dna Damage Response Proteins is Associated with Breast Cancer Subtype and Clinical Features
(Springer, 2011)
Landmark studies of the status of DNA damage checkpoints and associated repair functions in preneoplastic and neoplastic cells has focused attention on importance of these pathways in cancer development, and inhibitors of ...
Pregnancy-Associated Breast Cancer: Clinicopathological Characteristics of 20 Cases with A Focus On Identifiable Causes of Diagnostic Delay
(Karger, 2014)
Background: The primary objective of this study was to evaluate the clinicopathological characteristics of patients with pregnancy-associated breast cancer (PABC), with a special focus on diagnostic delays and the identifiable ...
Combined Long-Term Steroid And Immunosuppressive Treatment Regimen In Granulomatous Mastitis
(Karger, 2012)
Background: Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory disease of the breast. It is related to various etiological factors. The treatment of IGM is challenging as there is a lack of consensus in ...
Obesity Does Not Affect The Number Of Retrieved Lymph Nodes And The Rate Of Intraoperative Complications In Gynecologic Cancers
(Korean Soc Gynecology Oncology & Colposcopy, 2010)
Objective: Lymphadenectomy, in general, is a safe and well-tolerated procedure in gynecologic oncology. However, some technical difficulties may be experienced in obese women which may result in inadequate lymphadenectomy ...
Reduction of Qm Protein Expression Correlates with Tumor Grade in Prostatic Adenocarcinoma
(Nature Publishing Group, 2006)
The QM protein is a transcription cofactor inhibiting the activity of AP-1 transcription factors and is also a ribosomal protein participating in protein synthesis. While protein synthesis is known to be increased in many ...
Endometrial Cancer Risk Prediction Including Serum-Based Biomarkers: Results From The Epic Cohort
(Wiley-Blackwell, 2017)
Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimina-tion. Adding biomarker data to these models may improve predictive capacity; to our knowledge, ...
Concomitant Trastuzumab With Thoracic Radiotherapy: A Morphological And Functional Study
(Oxford Univ Press, 2011)
Background: The purpose of this study is to elucidate if there is an additive or supra-additive toxic effects of radiotherapy (RT) and trastuzumab (T) on vascular structures when used concomitantly. Methods: Female Wistar ...
Cpg Methylation In The Fhit Regulatory Region: Relation To Fhit Expression In Murine Tumors
(Nature Publishing Group, 2004)
To determine if: (1) 5' CpG island methylation is related to Fhit inactivation; (2) there are tumor or carcinogen-specific methylation patterns, we examined 35 CpG sites in the promoter, exon and intron 1 of the mouse Fhit ...
