Now showing items 1-10 of 78
Exome Sequencing Reveals Cubilin Mutation As A Single-Gene Cause Of Proteinuria
(Amer Soc Nephrology, 2011)
In two siblings of consanguineous parents with intermittent nephrotic-range proteinuria, we identified a homozygous deleterious frameshift mutation in the gene CUBN, which encodes cubulin, using exome capture and massively ...
Bilateral Germ Cell Cancer of The Testis: A Report of 11 Patients with a Long-Term Follow-Up
(Blackwell Science Ltd, 2000)
Objective To describe the incidence, clinical characteristics, treatment methods and long-term follow-up of bilateral germ cell tumours of the testis (GCTT) in patients treated at one institution. Patients and methods Of ...
Mutation Analysis Of Nphs1 In A Worldwide Cohort Of Congenital Nephrotic Syndrome Patients
Background: Congenital nephrotic syndrome (CNS) is defined as nephrotic syndrome that manifests within the first 3 months of life. Mutations in the NPHS1 gene encoding nephrin, are a major cause for CNS. Currently, more ...
Ultrastructural Effect Of Sildenafil Citrate On Corpus Cavernosum And Other Genital Organs In Female Rats
(Science China Press, 2003)
Aim: To determine the ultrastructural effects of sildenafil on the female genital organs. Methods: Twenty female cycling Wistar albino rats weighing 250 +/- 20 g were randomly divided into two groups of 10 each. Rats of ...
Reduction of Qm Protein Expression Correlates with Tumor Grade in Prostatic Adenocarcinoma
(Nature Publishing Group, 2006)
The QM protein is a transcription cofactor inhibiting the activity of AP-1 transcription factors and is also a ribosomal protein participating in protein synthesis. While protein synthesis is known to be increased in many ...
Ureteroneocystostomy In Primary Vesicoureteral Reflux: Critical Retrospective Analysis Of Factors Affecting The Postoperative Urinary Tract Infection Rates
(Brazilian Soc Urol, 2014)
Introduction: To determine the parameters affecting the outcome of ureteroneocystostomy (UNC) procedure for vesicoureteral reflux (VUR). Materials and Methods: Data of 398 patients who underwent UNC procedure from 2001 to ...
Unusual Metastases Of Renal-Cell Carcinoma
Proteasome Inhibitor Bortezomib Increases Radiation Sensitivity in Androgen Independent Human Prostate Cancer Cells
(Elsevier Science Inc, 2010)
OBJECTIVES To investigate the effects of a strong proteasome inhibitor, bortezomib alone or in combination with radiotherapy on androgen-independent DU145 human prostate cancer cells. Proteasomes play important roles in ...
Urothelium-Preserving Augmentation Cystoplasty Covered With A Peritoneal Flap
(Blackwell Science Ltd, 2000)
Objectives To present the results of bladder autoaugmentation covered with a peritoneal flap in patients with bladder dysfunction. Patients and methods Thirteen patients (seven male and six female, mean age 11.9 years, ...
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
(Taylor & Francis Ltd, 2012)
Background: There are few data on the effects of anesthesia and cardiopulmonary bypass (CPB) on perioperative renal function in children with cyanotic congenital heart disease undergoing open heart surgery. This study aims ...