Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Title
Now showing items 29-48 of 123
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Data The Dehp Induced Changes On The Trace Element And Mineral Levels In The Brain And Testis Tissues Of Rats
(2019)Di (2-ethylhexyl) phthalate (DEHP) is used as plasticizer in the industry and belongs to the phthalate family which can induce tissue damage including kidney, liver, and testis as a result of elevated oxidative stress ... -
Delipidation Of Plasma Has Minimal Effects On Human Butyrylcholinesterase
(2018)Human butyrylcholinesterase (BChE) is purified in large quantities from Cohn fraction IV-4 to use for protection against the toxicity of chemical warfare agents. Small scale preliminary experiments use outdated plasma from ... -
Determination Of Rivaroxaban In Human Plasma By Solid-Phase Extraction-High Performance Liquid Chromatography
(Oxford Univ Press, 2016)In this study, a solid-phase extraction (SPE)-high performance liquid chromatography (HPLC)-ultra violet (UV) method was developed for the determination of rivaroxaban (RIV), an oral anticoagulant drug, in human plasma ... -
Development And In Vitro Evaluation Of Pantoprazole-Loaded Microspheres
(Informa Healthcare, 2008)Pantoprazole is a proton pump inhibitor prodrug used in the treatment of gastric ulcers and gastroesophageal disease. Pantoprazole must be absorbed in the gastrointestinal tract and because it is unstable under acidic ... -
Development of Sensitive And Specific Analysis of Vildagliptin In Pharmaceutical Formulation By Gas Chromatography-Mass Spectrometry
(2015)A sensitive and selective gas chromatography-mass spectrometry (GC-MS) method was developed and fully validated for the determination of vildagliptin (VIL) in pharmaceutical formulation. Prior to GC-MS analysis, VIL was ... -
Development Of Titania Nanotube-Based Electrochemical Immunosensor And Determination Of Prostate Specific Antigen
(Japan Soc Analytical Chemistry, 2018)Early diagnosis of cancer is the most important factor that increases the success of treatment. Therefore, the development of new diagnostic tools is a necessity. In this study, a new electrode surface was developed via ... -
Diagnostic Implications Of Telomerase Activity In Pleural Effusions
(European Respiratory Soc Journals Ltd, 2003)The aim of the present study was to investigate the diagnostic efficacy of telomerase activity for discrimination of malignant and benign pleural effusions. Pleural effusions were collected from 109 consecutive patients ... -
Differential Requirement For The Atpase Domain Of The Cockayne Syndrome Group B Gene In The Processing Of Uv-Induced Dna Damage And 8-Oxoguanine Lesions In Human Cells
(Oxford Univ Press, 2002)Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include increased sensitivity ... -
Discrimination Of The Effects Of Doxorubicin On Two Different Breast Cancer Cell Lines On Account Of Multidrug Resistance And Apoptosis
(Indian Pharmaceutical Assoc, 2017)Breast cancer is one of the most common cancer types and malfunctioning proteins in apoptotic pathways are known to be the main contributors of cancer development. In this study MCF-7 and MDA-MB-231 breast cancer cell lines ... -
Dynamic Phosphometabolomic Profiling of Human Tissues and Transgenic Models By O-18-Assisted P-31 Nmr and Mass Spectrometry
(Amer Physiological Soc, 2012)Next-generation screening of disease-related metabolomic phenotypes requires monitoring of both metabolite levels and turnover rates. Stable isotope O-18-assisted P-31 nuclear magnetic resonance (NMR) and mass spectrometry ... -
Effect of Topically Applied Charged Particles on Healing of Colonic Anastomoses
(Amer Medical Assoc, 2002)Hypothesis: Various forms of electrical stimulation can improve wound healing in different tissues, but their application to gastrointestinal tract healing has not been investigated. We assumed that positively charged ... -
Effectiveness of Dimethylsulfoxide on The Survival and Volume Preservation of Autologous Fat Graft Tissue: A Preliminary Study
(Oxford Univ Press, 2016)Background: The survival of autologous fat graft tissue is dependent on various factors, such as vascularization and inflammation. Objective: This study aims to evaluate the possible beneficial effects of dimethylsulfoxide ... -
Effects Of Cadmium And Zinc Ions On Purified Lamb Kidney Cortex Glucose-6-Phosphate Dehydrogenase Activity
(Taylor & Francis Ltd, 2006)Glucose-6-phosphate dehydrogenase (G-6-PD) is the first enzyme in the pentose phosphate pathway. Cadmium is a toxic heavy metal that inhibits several enzymes. Zinc is an essential metal but overdoses of zinc have toxic ... -
Effects Of Rosiglitazone Treatment On The Pentose Phosphate Pathway And Glutathione-Dependent Enzymes In Liver And Kidney Of Rats Fed A High-Fat Diet
(Elsevier Science Inc, 2004)Background: Animals fed high-fat diets have been shown to develop hyperglycemia, insulin resistance, hyperlipidemia, and moderate obesity, which resemble the human metabolic syndrome. Obesity, the metabolic syndrome, and ... -
Effects Of Timolol Treatment On Pancreatic Antioxidant Enzymes In Streptozotocin-Induced Diabetic Rats: An Experimental And Computational Study
(2019)Background: The study aimed to investigate whether timolol-treatment has a beneficial effect on pentose phosphate pathway enzyme activities such as glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase ... -
Evaluation Of A Capillary Electrophoresis Method For Routine Determination Of Varenicline Tartrate In Quality-Control Laboratories
(Soc Chemists Technologists Madeconia, 2015)In this study, analyses were carried out on a fused-silica capillary (i.d. 50.0 mu m, total length 48.5 cm, and effective length 40.0 cm) in normal mode by applying a voltage of 20 kV. Sample injections were made in ... -
Evaluation Of Pharmaceutical Quality Of Conventional Dosage Forms Containing Paracetamol And Caffeine Available In The Turkish Drug Market
(Dissolution Technologies, Inc, 2016)The aim of this study was to evaluate the quality of conventional paracetamol- (PA) and caffeine- (CA) containing combined dosage forms in the Turkish drug market. For this purpose, weight variation, content uniformity, ... -
Fetal Allogeneic Umbilical Cord Cell Transplantation Improves Motor Function In Spinal Cord-Injured Rats
(Turkish Neurosurgical Soc, 2010)AIM: The objective of this study was to investigate whether the transplantation of fetal umbilical cord tissue cells as a source of stem cells into the acutely injured spinal cord would produce some regenerations and/or ...
