Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Title
Now showing items 67-86 of 123
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Lactoferrin In Gingival Crevicular Fluid And Peripheral Blood During Experimental Gingivitis
(2009)Objectives Lactoferrin (LF) is an iron binding protein and stored in the specific granules of granulocytes. It is released by degranulation following granulocyte activation. A positive correlation was previously reported ... -
Long-Term Effects Of Early-Life Antibiotic Exposure On Resistance To Subsequent Bacterial Infection
(2019)The gastrointestinal microbiota protects hosts from enteric infections; while antibiotics, by altering the microbiota, may diminish this protection. We show that after early-life exposure to antibiotics host susceptibility ... -
Low-Dose Bisphenol A Induces Ripk1-Mediated Necroptosis In Sh-Sy5Y Cells: Effects On Tnf-Alpha And Acetylcholinesterase
(2019)Bisphenol A (BPA) is an endocrine disruptor chemical, which is commonly used in everyday products. Adverse effects of its exposure are reported even at picomolar doses. Effects of picomolar and nanomolar concentrations of ... -
Methamidophos, Dichlorvos, O-Methoate And Diazinon Pesticides Used In Turkey Make A Covalent Bond With Butyrylcholinesterase Detected By Mass Spectrometry
(Wiley, 2010)Organophosphorus pesticides used most commonly in Turkey include methamidophos, dichlorvos, O-methoate and diazinon. These toxic chemicals or their metabolites make a covalent bond with the active site serine of ... -
Misincorporation Of Free M-Tyrosine Cytotoxic Mechanism For Oxidized A Into Cellular Proteins: A Potential Amino Acids
(Portland Press Ltd, 2006)In vitro studies demonstrate that the hydroxyl radical converts L-phenylalanine into in-tyrosine, an unnatural isomer of L-tyrosine. Quantification of m-tyrosine has been widely used as an index of oxidative damage in ... -
Modulation Of Mitochondrial Complex I Activity Averts Cognitive Decline In Multiple Animal Models Of Familial Alzheimer'S Disease
(2015)Development of therapeutic strategies to prevent Alzheimer's disease (AD) is of great importance. We show that mild inhibition of mitochondrial complex I with small molecule CP2 reduces levels of amyloid beta and phospho-Tau ... -
Molecular Fingerprints Of Hemoglobin On A Nanofilm Chip
(2018)Hemoglobin is an iron carrying protein in erythrocytes and also an essential element to transfer oxygen from the lungs to the tissues. Abnormalities in hemoglobin concentration are closely correlated with health status and ... -
Molecular Imprinted Based Quartz Crystal Microbalance Nanosensors For Mercury Detection
(2018)Mercury(II) ions are emerging as a result of more human activity, especially coal‐fired power plants, industrial processes, waste incineration plants, and mining. The mercury found in different forms after spreading around ... -
Molecular Imprinting Applications In Forensic Science
(2017)Producing molecular imprinting-based materials has received increasing attention due to recognition selectivity, stability, cast effectiveness, and ease of production in various forms for a wide range of applications. The ... -
Molecular Imprinting Of Macromolecules For Sensor Applications
(2017)Molecular recognition has an important role in numerous living systems. One of the most important molecular recognition methods is molecular imprinting, which allows host compounds to recognize and detect several molecules ... -
Molecularly Imprinted Biomimetic Surface Plasmon Resonance Sensor For Hormone Detection
(2019)In this study, 17 beta-estradiol (E2) was performed by surface plasmon resonance (SPR) based on molecularly imprinted technique. In the first, SPR sensor was prepared by the formation of E2 imprinted poly(2-hydroxyetyl ... -
Molecularly Imprinted Polymer Based Sensors For Medical Applications
(2019)Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In ... -
Molecularly Imprinted Polymer-Based Microfluidic Systems For Point-Of-Care Applications
(2019)Fast progress has been witnessed in the field of microfluidic systems and allowed outstanding approaches to portable, disposable, low-cost, and easy-to-operate platforms especially for monitoring health status and point-of-care ... -
Monitoring The Perturbation Of Soil And Groundwater Microbial Communities Due To Pig Production Activities
(Amer Soc Microbiology, 2013)This study aimed to determine if biotic contaminants originating from pig production farms are disseminated into soil and groundwater microbial communities. A spatial and temporal sampling of soil and groundwater in proximity ... -
Monoamine Oxidase Inhibitory Activity Of Novel Pyrazoline Analogues: Curcumin Based Design And Synthesis
(Amer Chemical Soc, 2016)A series of new 2-methoxy-4-(5-pheny1-4,5dihydro-1H-pyrazol-3-yl)phenolderivatives, 4-13, were synthesized and tested for their human MAO inhibitory activity. All the compounds were found to be selective and reversible ... -
Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins And Peptides Independent Of Surrounding Amino Acids
(Amer Chemical Soc, 2017)Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are irreversibly inhibited by organophosphorus pesticides through formation of a covalent bond with the active site serine. Proteins that have no active site ... -
Morphologic And Mechanical Characteristics Of Engineered Bovine Arteries
(Mosby-Elsevier, 2001)Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro ...
