Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Title
Now showing items 81-100 of 123
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Molecularly Imprinted Polymer Based Sensors For Medical Applications
(2019)Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In ... -
Molecularly Imprinted Polymer-Based Microfluidic Systems For Point-Of-Care Applications
(2019)Fast progress has been witnessed in the field of microfluidic systems and allowed outstanding approaches to portable, disposable, low-cost, and easy-to-operate platforms especially for monitoring health status and point-of-care ... -
Monitoring The Perturbation Of Soil And Groundwater Microbial Communities Due To Pig Production Activities
(Amer Soc Microbiology, 2013)This study aimed to determine if biotic contaminants originating from pig production farms are disseminated into soil and groundwater microbial communities. A spatial and temporal sampling of soil and groundwater in proximity ... -
Monoamine Oxidase Inhibitory Activity Of Novel Pyrazoline Analogues: Curcumin Based Design And Synthesis
(Amer Chemical Soc, 2016)A series of new 2-methoxy-4-(5-pheny1-4,5dihydro-1H-pyrazol-3-yl)phenolderivatives, 4-13, were synthesized and tested for their human MAO inhibitory activity. All the compounds were found to be selective and reversible ... -
Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins And Peptides Independent Of Surrounding Amino Acids
(Amer Chemical Soc, 2017)Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are irreversibly inhibited by organophosphorus pesticides through formation of a covalent bond with the active site serine. Proteins that have no active site ... -
Morphologic And Mechanical Characteristics Of Engineered Bovine Arteries
(Mosby-Elsevier, 2001)Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro ... -
Neurotoxic Effects Of Bisphenol A On Sh-Sy5Y Neuroblastoma Cells Via Nitric Oxide
(2019)Bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl)propane)polycarbonate is an industrial component frequently used as an additive in the construction of epoxy resin and other non-polymer plastics. In this study cytotoxicity of low ... -
Non-Enzymatic Electrochemical Sensing Of Malathion Pesticide In Tomato And Apple Samples Based On Gold Nanoparticles-Chitosan-Ionic Liquid Hybrid Nanocomposite
(2018)Malathion (MLT) is an organophosphorous type pesticide and having seriously high toxicity and electrochemical platforms for rapid, simple, inexpensive and sensitive determination of pesticides is still a special concern. ... -
Nucleotide Excision Repair By Dual Incisions In Plants
(Natl Acad Sciences, 2016)Plants use light for photosynthesis and for various signaling purposes. The UV wavelengths in sunlight also introduce DNA damage in the form of cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts ... -
Optimization Of A Gas Chromatography-Mass Spectrometry Method Using Chemometric Techniques For The Determination Of Ezetimibe In Human Plasma
(Scientific Technical Research Council Turkey-Tubitak, 2013)A new, rapid, and sensitive gas chromatography-mass spectrometry (GC-MS) method was developed for the determination of ezetimibe (EZE) in human plasma. EZE was derivatized prior to GC-MS analysis. Various derivatization ... -
P-31 Nmr Correlation Maps Of O-18/O-16 Chemical Shift Isotopic Effects For Phosphometabolite Labeling Studies
(Springer, 2011)Intramolecular correlations among the O-18-labels of metabolic oligophosphates, mapped by J-decoupled P-31 NMR 2D chemical shift correlation spectroscopy, impart stringent constraints to the O-18-isotope distributions over ... -
Plasma 8-Isopgf2 Alpha and Serum Melatonin Levels in Patients with Minimal Cognitive Impairment and Alzheimer Disease
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with ... -
Poly-(L)-Histidine Immobilized Cryogels for Lysozyme Purification
(Sage Publications Inc, 2016)Immobilized metal ion affinity chromatography is one of the methods used for the adsorption of proteins. In this study, poly(glycidyl methacrylate) cryogel discs were prepared by free radical polymerization. The metal ... -
Polyproline Tetramer Organizing Peptides in Fetal Bovine Serum Acetylcholinesterase
(Elsevier Science Bv, 2013)Acetylcholinesterase (AChE) in the serum of fetal cow is a tetramer. The related enzyme, butyrylcholinesterase (BChE), in the sera of humans and horse requires polyproline peptides for assembly into tetramers. Our goal was ... -
Proguanil Metabolism in Relation To S-Mephenytoin Oxidation in A Turkish Population
(Blackwell Science Ltd, 1996)The oxidation of proguanil was studied in 89 unrelated healthy Turkish volunteers after administration of proguanil (single dose, 200 mg, orally). Based on the distribution of the ratio of proguanil to cycloguanil excreted ... -
Regeneration and Healing of Bone and Cartilage in Type-1 and Type-2 Diabetes: The Effects of Insulin
(Tubitak Scientific & Technical Research Council Turkey, 2016)Increased fragility of long bones and delay in fracture healing in adults as well as skeletal development disorders in children are thought to be associated with endochondral ossification problems. The extracellular matrix ... -
Role of Serotonin in the Regulation of Renal Proximal Tubular Epithelial Cells
(Taylor & Francis Ltd, 2016)In various renal injuries, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors, such as serotonin, are released into microenvironment upon platelet activation following renal ... -
Rp-Hplc Method Development and Validation for Estimation of Rivaroxaban in Pharmaceutical Dosage Forms
(Univ Sao Paulo, Conjunto Quimicas, 2013)Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in ... -
Rutin Ameliorates Methotrexate Induced Hepatic Injury in Rats
(Acta Cirurgica Brasileira, 2015)PURPOSE: To investigate the possible protective effect of rutin on methotrexate induced hepatotoxicity in rats. METHODS: Twenty-two rats were divided into three experimental groups; Control-saline, Mtx, Mtx+Rutin. Hepatic ...
