Alzheimer Bakım Verenlerine Uygulanan Çok Bileşenli Destek Programlarının Bakım Yükü Üzerine Etkisi: Sistematik Derleme ve Meta Analiz Çalışması
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Date
2023-10-16Author
Şentürk Kılıç, Betül
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Şentürk Kılıç, B., The Effectiveness of Multi-Component Support Programs for
Alzheimer’s Caregivers on Burden: A Systematic Review and Meta-Analysis,
Hacettepe University Graduate School of Health Sciences Ph.D. Dissertation in
Psychiatric Nursing, Ankara, 2024. This systematic review and meta-analysis
aimed to evaluate the effectiveness of multi-component support programs on the
caregiver burden of individuals caring for Alzheimer’s patients. The research was
conducted through searches in five databases (CENTRAL, CINAHL, PsycINFO,
PubMed, WOS) from October 18 to November 28, 2021, and included Englishlanguage randomized controlled trials that met the inclusion criteria. Two researchers
independently assessed the full-text reviews, risk of bias using the Cochrane 'Risk of
Bias-2' tool, and evidence quality using the GRADE tool. Additional information
was obtained by contacting study authors, and analyses were conducted when
sufficient data were provided. Results were presented narratively in cases of
insufficient data. The review included 8 studies overall, with 6 of these studies
providing data on caregiver burden outcomes that were incorporated into the meta
analysis. Among the 1147 participants, only one study was web-based, while the
other seven interventions were conducted face-to-face. The components of the
interventions were mainly educational, supportive, and skill-building, with only one
intervention including respite care. Overall risk of bias assessment recorded one
study with high risk, four with unclear risk, and one with low risk. The effect sizes of
the interventions were calculated based on the means and standard deviations of
caregiver burden scores before and after the intervention, as well as follow-up
measurements. The multi-component intervention programs were found to have an
uncertain short-term effect (Cohen's d = 0.12; 95% CI: -0.06 - 0.29; p = 0.39) but
were effective in the long term (Cohen's d = 0.21; 95% CI: 0.03 - 0.38; p = 0.02).
The certainty of evidence for caregiver burden outcomes was determined to be low
before the intervention and follow-up, and very low from pre-intervention to postintervention measurements. The data is current as of 12/12/2023. Multi-component
support programs are effective in reducing caregiver burden for Alzheimer's
caregivers in the long term; however, more high-quality studies are needed to
confirm this effectiveness.