Temel Tıp Bilimleri Bölümü Tez Koleksiyonu
Recent Submissions
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Deneysel Parkinson Hastalığı Modelinde Mitokondri Transplantasyonu ve Egzersizin Etkilerinin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2024-10-11)Parkinson's disease (PD) is associated with degeneration of dopamine-secreting neurons in the brain. PD manifests itself with impaired locomotor and spontaneous activities, such as difficulty initiating movement, tremors, ... -
Evaluation Of Recombinational Dna Damage Response In Castration-Resistant Prostate Cancer And Investigation Of The Combined Effect Of Rad51 And Wee1 Inhibitors On Radiosensitivity
(Sağlık Bilimleri Enstitüsü, 2014-09)Castration-resistant prostate cancer (mCRPC) is a disease with a poor prognosis. Recently, DNA repair mechanisms have been targeted in new treatment regimens, in particular inpatients carrying mutations in the genes of DNA ... -
Yapısal Eşitlik Modellerinde Aracı ve Düzenleyici Etkilerin Modellenmesi
(Sağlık Bilimleri Enstitüsü, 2024)Structural Equation Modeling (SEM) is a powerful analytical method frequently used in social sciences, yet it is relatively less preferred in the health scinces due to its large sample size requirements and the more ... -
Karaciğer Biyopsisi Yapılmış Hastaların Ön Tanı Ve Son Tanılarının Retrospektif Olarak Değerlendirilmesi
(Tıp Fakültesi, 2024-05)Introduction and Purpose: Although non-invasive tests are increasingly used in the evaluation of liver pathologies, liver biopsy continues to have an important role in the diagnosis of liver diseases. This study aimed ... -
OTOMATİK MADDE ÜRETİMİNİN AİLE HEKİMLİĞİ ALANINA UYGULANMASI VE ÜRETİLEN MADDELERİN NİTELİĞİNİN İNCELENMESİ
(Sağlık Bilimleri Enstitüsü, 2024-08-29)Multiple-choice items form the basis of many assessments used in medical education. Writing questions using traditional approaches is, however, a time-consuming and challenging process. Therefore, the primary aim of this ... -
AFET YÖNETİMİNDE SAĞLIK HİZMETLERİNDE ETİK: ULUSAL MEDİKAL KURTARMA EKİBİ (UMKE) ANKARA ÖRNEĞİ
(Sağlık Bilimleri Enstitüsü, 2024-08-09)It is very important to pay attention to disaster ethics at all stages of the disaster management process. The objective of this study are to explore the experiences of health professionals voluntarily engaged in UMKE ... -
KADIN DOĞUM HEKİMLERİNİN, PRENATAL TARAMA VE SÜREÇ YÖNETİMİNDEKİ TUTUM VE DAVRANIŞLARININ TIP ETİĞİ AÇISINDAN DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2024-08-12)Türkçapar AF, Evaluation of Attitudes and Behaviour of Obstetricians in Prenatal Screening and Process Management in Terms of Medical Ethics. Hacettepe University, Graduate School of Health Sciences, Medical Ethics and ... -
Acil tıp eğitiminde tanısal güvenlik odaklı eleştirel düşünme modülü eğitim programının geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2024)Diagnostic errors often relate to suboptimal decisions in clinical reasoning and decision-making steps, such as insufficient assessment, the presence of inadequate or incorrect assumptions, incorrect or incomplete evaluation ... -
AFET YÖNETİMİNDE SAĞLIK HİZMETLERİNDE ETİK: ULUSAL MEDİKAL KURTARMA EKİBİ (UMKE) ANKARA ÖRNEĞİ
(Sağlık Bilimleri Enstitüsü, 2024-08-13)It is very important to pay attention to disaster ethics at all stages of the disaster management process. The objective of this study are to explore the experiences of health professionals voluntarily engaged in UMKE ... -
LABORATUVAR YAPIMI BİR PCR YÖNTEMİ İLE MYCOBACTERIUM TUBERCULOSIS KOMPLEKSİNİN SAPTANMASI
(Sağlık Bilimleri Enstitüsü, 2024)Tato, V. Detection of Mycobacterıum tuberculosis Complex by A Laboratory-Made Polymerase Chain Reaction (PCR) Method. Hacettepe University Graduate School of Health Sciences, PhD Thesis in Microbiology, Ankara, 2024. The ... -
KORTİKAL YAYILAN DEPOLARİZASYON İLE TETİKLENEN NÖRO-PARAİNFLAMASYONDA NLRP2 İNFLAMAZOMUNUN ROLÜ
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2024)Migraine is a common headache syndrome in the general population. Inflammation resulting from activation of the trigeminovascular system plays an important role in its pathophysiology. Cortical spreading depolarization ... -
Birleştirilmiş Tanı Testlerine Meta Analitik Yaklaşımlar
(Sağlık Bilimleri Enstitüsü, 2024-07-29)Aydın, M., Meta Analytic Approaches for Incorporated Diagnostic Tests. Hacettepe University Graduate School of Health Sciences, Ph.D. Thesis in Biostatistics, Ankara, 2024. Depending on the developments in science and ... -
Yenidoğan Sıçanlarda Ketaminle Oluşturulan Nörotoksisiteye Deksmedetomidinin Koruyucu Etki Mekanizmalarının İncelenmesi
(Tıp Fakültesi, 2024)Neurotoxicity caused by the repeated or long-term administration of anesthetics and sedatives during the neurodevelopmental period, leading to behavioral and cognitive impairments, continues to be a matter of concern. This ... -
Tek Yönlü Bağımsız Grup Tasarımı için Varyans Homojenliği Testleri
(Sağlık Bilimleri Enstitüsü, 2024)In this thesis, a comparison of Type I error rates and power values for 20 different variance homogeneity test methods was conducted using a Monte Carlo simulation approach. This was done to assess the homogeneity of the ... -
Immunomodulatory Effects of Novel Immune Costımulator Sa-4-1bbl In Nnk-Induced Lung Cancer Preclınıcal Model
(Sağlık Bilimleri Enstitüsü, 2024-07-09)Immune checkpoint inhibitors hold promise in treating various malignancies, but their use is limited due to side effects and treatment resistance. Therefore, the immune costimulation pathway is an important target to enhance ... -
Mekanosensitif İyon Kanalı Adayı Genlerin Astacus Leptodactylus Türünde Klonlanması ve İlgili Proteinlerin Fonksiyonel ve Yapısal Özelliklerinin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2024-07-10)Cells respond to various mechanical stimuli like tension or osmotic pressure changes in the membrane. Mechanosensitive ion channels play an important role in mechanotransduction, which is the conversion of mechanical stimuli ... -
Bir İlde Kamuda Görevli Sağlık Çalışanlarının İş Güvenliği İklimi ve İş Yerinde COVID-19 Yakın Temaslı Olma Durumunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-07-05)Healthcare workers frequently come into high-risk contact with COVID-19 cases. In other words, they are being in close contact with COVID-19. This study examined the relationship between healthcare workers' close contact ... -
Etik İnceleme Düzeyleri Açısından İnsanı Geliştirme Etiği Çalışmalarının Dağılımı: Bir Kapsam İncelemesi
(Sağlık Bilimleri Enstitüsü, 2024)In this study, it was aimed to evaluate the HEE literature in terms of the distribution of the levels of ethical discourse with the scoping review method. For this purpose, 325 articles were examined in detail following ... -
Türk Kızılay Afet Personelinin Küresel İklim Değişikliği Bilgilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-06)This study aimed to evaluate the knowledge of Turkish Red Crescent disaster personnel regarding global climate change. The research was a descriptive epidemiological study, and the participation rate was 30.3%. Data were ... -
Servikal Posterior Laminoforaminotomi (Key-Hole) Yöntemi ile Cerrahi Yaklaşımda Vertebral Oluşumların İşaret Noktalarının Anatomik ve Radyolojik Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-05-30)The cervical portion of the vertebral column, due to its delicate structure, is vulnerable to pathologies such as cervical disc herniations attributed to its high mobility and biomechanical loading. While anterior cervical ...