Temel Tıp Bilimleri Bölümü Tez Koleksiyonu
Recent Submissions
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Endometrial Stromal Hücrelerde Ovaryan Hormonlar ile CKAP4 İlişkisinin İncelenmesi
(Tıp Fakültesi, 2023)Endometrial stromal cells undergo changes in the menstrual cycle and decidualization with the effect of ovarian hormones. Disruptions in these processes may result in clinical outcomes such as infertility, recurrent pregnancy ... -
Glikoprotein Non-Metastatik Melanoma Protein B (GPNMB), Kan Glukoz Düzeyi ve Karaciğer Yağlanması Arasındaki İlişkinin İncelenmesi
(Tıp Fakültesi, 2023)Although the functions and role of GPNMB, which has been shown to be secreted from the liver and accepted as a hepatokine, and its role in energy balance are not yet known, it is thought to play a role in the ... -
DIŞKI VE MİDE BİYOPSİ ÖRNEKLERİNDEN HELICOBACTER PYLORI ENFEKSİYONUNUN VE KLARİTROMİSİN DİRENCİNİN MOLEKÜLER YÖNTEMLER İLE SAPTANMASI
(Tıp Fakültesi, 2022)Inal Neşe, Detection of Helicobacter pylori Infection and Clarithromycin Resistance in Stool and Gastric Biopsy Samples by Molecular Methods, Hacettepe University Faculty of Medicine, Department of Medical Microbiology, ... -
Aksaray Üniversitesi Sağlık Bilimleri Fakültesi Öğrencilerinin Afet Bilinci Algılarının ve Tutumlarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Akil, K., Evaluation of Disaster Consciousness Perceptions and Attitudes of Aksaray University Faculty of Health Sciences Students. Hacettepe University, Graduate School of Health Sciences, Master of Science Thesis for ... -
Kalıtsal Metabolik Hastalıklarda Otofaji, Oksidatif Stres ve İnflamasyon İlişkisi
(Sağlık Bilimleri Enstitüsü, 2023-08)The complications such as epilepsy, cataract, hepatic failure, chronic renal disease may develop during the clinical follow-up of the patients with inherited metabolic diseases. The aim of this study is to investigate the ... -
SİTOKROM P450 2C19 (CYP2C19) GENETİK POLİMORFİZMLERİNİN ÜLSERATİF KOLİT VE CROHN HASTALIĞINDAKİ ETKİLERİ
(Sağlık Bilimleri Enstitüsü, 2023)Inflammatory bowel diseases (IBD) are diseases characterized by chronic inflammation of the intestinal mucosa. Ulcerative colitis (UC) and Crohn's disease (CH) are clinical entities presenting different characteristics. ... -
PANDEMİ DÖNEMİNDE BAŞKENT ÜNİVERSİTESİ TIP FAKÜLTESİ ÖĞRENCİLERİNİN ÖĞRENME YAKLAŞIMLARIYLA PSİKOLOJİK DURUMLARI ARASINDAKİ İLİŞKİ VE PSİKOLOJİK SAĞLAMLIĞIN ARACILIK ROLÜ
(Sağlık Bilimleri Enstitüsü, 2023)In this study, it was aimed to evaluate the mediating role of resilience in the relationship between the learning approaches and psychological states of Başkent University Faculty of Medicine students during the pandemic ... -
L-arjinin ve Agmatinin İnsan NCI-H716 Hücrelerinde GLP-1 ve PYY Salgısı Üzerine Etkisi: Kalsiyum Algılayan Reseptörlerin Rolü
(Sağlık Bilimleri Enstitüsü, 2023-08-14)Agmatine is a natural polyamine produced from L-arginine by arginine decarboxylase and is abundant in foods. One of the most significant effects of glucagon like peptide-1 (GLP1) and peptide YY (PYY) hormones released ... -
Stattic ve/veya Paclitaxel’in Üçlü Negatif Meme Kanseri Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2023-08)Triple negative breast cancer (TNBC) is an invasive and metastatic cancer with aggressive progress. We aimed to investigate the in vitro and in vivo antiproliferative and in vivo antimetastatic effects of Paclitaxel, used ... -
Boruta ve Elastik Ağ Algoritmalarının Gen Seçim Performanslarının RNA Dizileme Veri Setleri Üzerinde Karşılaştırılması: Bir Monte Carlo Benzetim Çalışması
(Sağlık Bilimleri Enstitüsü, 2023-08-24)Boruta Algorithm and Determan's Algorithm in Elastic Net Generalized Linear Models were applied to select the genes that have a significant effect on the related cancer disease using eight real RNA sequencing data set ... -
SPECIFYING THE BOUNDARIES OF GRAY ZONE IN DIAGNOSTIC TESTS WITH INFORMATION CRITERIA
(Sağlık Bilimleri Enstitüsü, 2023-08-09)The decision-making process in medicine is a crucial subject due to the classification of subjects as healthy or diseased. Mostly, it concludes with binary outcomes, such as whether the person has a condition or not. The ... -
Cloning Putative Voltage-Gated Calcium Channel Gene in Astacus Leptodactylus and Determination of Structural and Functional Properties of Related Protein
(Sağlık Bilimleri Enstitüsü, 2023)Voltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the ... -
SMN EKSİKLİĞİNDE RHO-İLİŞKİLİ PROTEİN KİNAZIN (ROCK) MİKROTÜBÜL STABİLİTESİ ÜZERİNE ETKİSİNİN ARAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2023-07)Spinal muscular atrophy (SMA) is one of the rare genetic diseases with an autosomal recessive inheritance. SMA is involved in both neurodegenerative and neuromuscular disease groups due to the loss of α motor neurons in ... -
Pediatrik Büyüme Eğrilerinin Model Performanslarının Gamlss Yöntemi ile İncelenmesi ve Kantil Regresyon Yöntemi ile Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2023-07-12)Reference pediatric growth curves constructed with the help of anthropometric measurements are one of the best tools in the examination of a child's growth and development, in the early diagnosis of disease status and in ... -
Psöriasis, Kutanöz Lupus Eritematozus ve Liken Skleroz Histopatolojilerinde Kannabinoid 1 Reseptörü (CB1) ve N-Arachidonoylethanolamine (AEA)’nın Yapım ve Yıkım Enzimlerinin Varlığının Araştırılması
(Tıp Fakültesi, 2023)The endocannabinoid system, has many functions with its enzymes, ligands and receptors. It’s first discovered receptor is CB1r and the most researched ligand is N-arachidonoylethanolamine (AEA). One of the enzymes involved ... -
Periodontitise Yatkınlıkta Rol Oynadığı Düşünülen RSPO4 Genine Ait Putatif Bir Düzenleyici Bölgenin Gen İfadesini Hızlandırıcı Etkisinin Gösterilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Periodontitis is one of the complex diseases characterized by the destruction of tooth-specific supporting structures in which genetic, environmental and lifestyle factors play a role, and the genetic mechanisms associated ... -
Ankara İli Etimesgut İlçesinde Yer Alan Aile Sağlığı Merkezlerinde Görev Yapan Sağlık Çalışanlarının Aşılama Hakkındaki Bilgi, Görüş ve Davranışları
(Sağlık Bilimleri Enstitüsü, 2023)Özaltun Ş.C., Knowledge, Thoughts, and Behaviors of Healthcare Workers Regarding Vaccination in Family Health Centers in Etimesgut District of Ankara, Hacettepe University Graduate School of Health Sciences Vaccinology ... -
Ailevi Akdeniz Ateşi Hastalarında Otoenflamasyonun İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)Familial Mediterranean Fever (FMF) is the most common autoinflammatory disease. The aim of this study is to determine the changes of GSDMD, IL-1B, and IL-18 in disease attacks of FMF and to compare their levels in the ... -
Primer İmmün Yetmezlikler-İşlevsel Çözümleme
(Çocuk Sağlığı Enstitüsü, 2023-06)Primary immunodeficiency diseases are rare diseases with a wide spectrum due to the increasing the number of new mutations defined to cause these diseases. Besides the clinical and laboratory manifestations, the genetic ... -
Propriyosepsiyon ve Denge Kontrolü ile El İkinci ve Dördüncü Parmakların Uzunluk Oranı Arasındaki İlişkinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-07-03)Prenatal exposure to testosterone is known to play an important role in the development of the fetal nervous system, genitourinary system and finger length. Specifically, prenatal testosterone exposure leads to an increase ...