There is a need for treatment options with a rapid onset of action and fewer side effects that can be used in the acute treatment of anxiety disorders. To meet this need, the anxiolytic-like effect of Salvia heldreichiana, ...

It has been observed in recent years that the age of onset of puberty has shifted earlier, particularly in girls. Although obesity is regarded as one of the factors contributing to this situation, the link between prepubertal ...

In this study, our aim was to investigate the effect of 12/15 LOX inhibition on neuroinflammation process. For this purpose, two different cerebral ischemia models in mouse, permanent ischemia and ischemia/recanalization ...

The cervical portion of the vertebral column, due to its delicate structure, is vulnerable to pathologies such as cervical disc herniations attributed to its high mobility and biomechanical loading. While anterior cervical ...

Circadian rhythms are biological processes that occur through the regulation of gene expression over time. These processes influence many biological processes such as the sleep and wake cycle, hormonal release, metabolism ...

Spinal muscular atrophy (SMA) is one of the rare genetic diseases with an autosomal recessive inheritance. SMA is involved in both neurodegenerative and neuromuscular disease groups due to the loss of α motor neurons in ...

Especially, in recent years, the use of social network analysis has gained interest in biomarker discovery studies. Hybrid approaches involve social network analysis as a step of the feature selection process bring a ...

Spinal muscular atrophy (SMA), which is characterized by motor neuron loss and muscle atrophy, is a neurodegenerative disease primarily in childhood. In SMA, Survival of motor neuron 1 (SMN1) gene mutations lead to the ...

Childhood- onset spinal muscular atrophy (SMA) is an autosomal recessive disorder, which leads to alpha motor neuron degeneration. Although 95-98 % of the patients have homozygous deletions in exon 7 and 8 SMN1 gene, ...

Triple negative breast cancer (TNBC) is an invasive and metastatic cancer with aggressive progress. We aimed to investigate the in vitro and in vivo antiproliferative and in vivo antimetastatic effects of Paclitaxel, used ...