Although it is known that capillary pericytes function in the regulation of capillary tone and blood flow, the contractile proteins involved in these processes are unidentified. It is likely that α-SMA functions as a part ...

Ischemic stroke results in sudden blood flow cessation thus leads to sudden onset unmet energy requirements. Although the clotted artery is recanalized and blood flow is restored back, brain perfusion may not be sustained ...

Dystonia, which is the third most common movement disorder, is a heterogeneous group of diseases both etiologically and pathophysiologically. Striatal cholinergic dysfunction is a common pathophysiologiccal mechanism ...

One of the critical limitations of the studies examining the effects of neuro-inflammation on depression is not implementing a protocol compatible with the pathophysiology of primary depression instead of using a protocol ...

Several findings suggest that the brain energy demand is mostly localized at the synapses, and glycogen in the perisynaptic astrocytic endfeet serves as the main actor that matches the synaptic energy supply and demand. ...

ABSTRACT Yavas, I. The Effect of Neopterin Level and Kynurenine Pathway on Inflammation and Neurodegeneration in Patients with Multiple Sclerosis and Parkinson's. Hacettepe University Graduate School Health Sciences ...

Hemophagocytic syndromes are rare, life-threatening conditions characterized by hypercytokinemia, systemic inflammation, and overstimulation of the immune system leading to multi-organ failure. Primary Hemophagocytic ...

Gurler, G., The Investigation the Role of Reduced Folate Carrier 1 in the Models of Ischemic Stroke and Retinal Ischemia, Hacettepe University, Graduate School of Health Sciences, Neuroscience Program, Doctor of Philosophy ...

There is ample evidence for the role of inflammatory signaling pathways in depression. However, in these studies, depression was modeled either by bacterial endotoxins or by acute stress, usually studied only in male animals ...

Ünal D. The Effects Of Neuroinflamation On Synaptic Plasticity In Autism Spectrum Disorders, Hacettepe University Graduate School of Health Sciences Basic Neurological Sciences (Neuroscience) Program, Doctor of ...